|
T6164 |
Ciproxifan
|
FUB-359 |
Histamine Receptor
|
|
Ciproxifan (FUB-359) is a highly effective and specific histamin H3-receptor antagonist (IC50: 9.2 nM). |
|
T41247 |
Thioperamide maleate
|
MR-12842 maleate |
Histamine Receptor
|
|
Thioperamide maleate (MR-12842 maleate) is an effective and selective antagonist of H3 receptor (Ki = 4.3 nM) for inhibition of [3H]histamine synthesis (Ki = 31 nM). |
|
T22864 |
Immethridine dihydrobromide
|
|
Others
|
|
Immethridine dihydrobromide is a histamine H3 receptor agonist. |
|
T10499 |
H3 receptor-MO-1
|
|
Histamine Receptor
|
|
H3 receptor-MO-1 is a potent modulator of the histamine H3 receptor (H3 receptor) and can be used to study neurodegeneration and cognitive disorders. |
|
T27678 |
JNJ-39220675
|
JNJ39220675 |
|
|
JNJ-39220675, a selective histamine H3 receptor antagonist, reduces the abuse-related effects of alcohol in rats. |
|
T79500L |
KSK94 FA
|
KSK94 FA(2566716-07-0 Free base) |
Histamine Receptor
|
|
KSK94 FA is a potent histamine H3 receptor antagonist that inhibits H3 receptors and is used in the study of neuropathic pain and obesity. |
|
T67828 |
Enerisant
|
TS-091 |
Histamine Receptor
|
|
Enerisant (TS-091) is an orally active, selective and potent histamine H3 receptor antagonist that modulates histamine H3 receptors in mice in a dose-dependent manner.Enerisant promotes pro-cognitive effects and reverses... |
|
TQ0066 |
GSK189254A
|
GSK189254 |
Histamine Receptor
|
|
GSK189254A (GSK189254) is a potent and specific histamine H3 receptor antagonist (pKi values: 9.59-9.90 and 8.51-9.17 for human and rat H3). |
|
T8822 |
JNJ-5207852 dihydrochloride
|
|
Histamine Receptor
|
|
JNJ-5207852 dihydrochloride is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor. |
|
T7413 |
JNJ-5207852
|
|
Histamine Receptor
|
|
JNJ-5207852 is a novel, non-imidazole histamine H3 receptor antagonist, with high affinity at the rat (pKi=8.9) and human (pKi=9.24) H3 receptor. |
|
T7176 |
Pitolisant hydrochloride
|
BF 2649,Ciproxidine |
Histamine Receptor
|
|
Pitolisant hydrochloride (Ciproxidine) is a potent and selective inverse agonist of the histamine H3 receptor(Ki : 0.16 nM). |
|
T60636 |
Pitolisant
|
|
|
|
Pitolisant is a potent and selective nonimidazole inverse agonist that acts on the recombinant human histamine H3 receptor with Ki of 0.16 nM. |
|
T77593 |
KSK67
|
|
Sigma receptor
|
|
KSK67 is a selective dual antagonist of sigma-2 and histamine H3 receptors with inhibitory effects on H3 receptors, sigma-1, and sigma-2 receptors, with Ki values of 3.2, 1531, and 101 nM, respectively.KSK67 can be used ... |
|
T79499 |
KSK68
|
|
Histamine Receptor
|
|
KSK68 is a potent dual sigma-1 and histamine H3 receptor antagonist with potential analgesic activity and high affinity for H3 receptors, sigma-1, sigma-2 receptors.KSK68 can be used in the study of pain related diseases... |
|
T16476 |
PF-03654746
|
|
Histamine Receptor
|
|
PF-03654746 is a selective antagonist of the histamine H3 receptor. PF-03654746 improves cognitive efficacy and disease-modifying effects in Alzheimer's disease. PF-03654746 can be used in studies about the treatment of ... |
|
T70489 |
Enerisant HCl
|
|
P450
,
Histamine Receptor
|
|
Enerisant HCl is a novel potent and selective histamine H3 receptor antagonist, a substrate for P-gp, mediated by cytochrome P450 (CYP) and transporter proteins. |
|
T12054L |
MK-0249 FA
|
MK-0249 FA(862309-06-6 Free base) |
Histamine Receptor
|
|
MK-0249 FA is an orally active, selective and potent histamine H3 inverse agonist for the study of attention deficit, hyperactivity disorder neurodivergent and cognitive disorders in adults. |
|
T14087 |
ABT-239
|
|
TRP/TRPV Channel
|
|
ABT-239 is a novel, highly efficacious antagonist belonging to the non-imidazole class of histamine H3 receptor (H3R) antagonists. It also acts as a transient receptor potential vanilloid type 1 (TRPV1) antagonist. |
|
T32191 |
Irdabisant
|
CEP-26401,CEP 26401,CEP26401 |
Histamine Receptor
|
|
Irdabisant (CEP-26401) (CEP-26401) is a selective, orally active and blood-brain barrier (BBB) penetrant antagonist/inverse agonist of histamine H3 receptor (H3R) (rat H3R Ki= 7.2 nM, human H3R Ki= 2.0 nM). Irdabisant ex... |
|
T0246 |
Betahistine dihydrochloride
|
PT-9,Betahistine 2HCl |
Histamine Receptor
|
|
Betahistine dihydrochloride (Betahistine 2HCl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. |
|
T0246L |
Betahistine mesylate
|
Extovyl,Melopat,Meginalisk |
Histamine Receptor
|
|
Betahistine mesylate (Extovyl) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. |
|
T8514 |
LML134
|
LML-134 |
Histamine Receptor
|
|
LML134 (LML-134) is an inverse agonist of Histamine 3 receptor (H3R)(hH3R cAMP and hH3R bdg with Kis of 0.3 nM and 12 nM). |
|
T4195 |
Betahistine
|
PT 9 base,Vasomotal,Serc base |
Histamine Receptor
|
|
Betahistine (Vasomotal) is a histamine analog and H1 receptor agonist that serves as a vasodilator. It is used in MENIERE DISEASE and in vascular headaches but may exacerbate bronchial asthma and peptic ulcers. Betahisti... |
|
T1232 |
Mepyramine maleate
|
Pyrilamine maleate |
Histamine Receptor
|
|
Mepyramine maleate (Pyrilamine maleate) is a histamine H1 antagonist. It has mild hypnotic properties and some local anesthetic action and is used for allergies (including skin eruptions) both parenterally and locally. I... |
|
T23519 |
VUF 5681 dihydrobromide
|
|
Others
|
|
histamine H3 receptor silent antagonist |
|
T23456 |
Thioperamide
|
|
Others
|
|
histamine H3 and H4 antagonist/inverse agonist |
|
T14970 |
Cipralisant
|
GT-2331 |
Others
|
|
Cipralisant is a selective histamine H3 receptor antagonist in vivo, and an agonist in vitro (pKi: 9.9 for histamine H3 receptor; Ki: 0.47 nM for rat histamine H3 receptor). It has the potential for the treatment of atte... |
|
T10911 |
H3 receptor antagonist 1
|
|
Histamine Receptor
|
|
H3 receptor antagonist 1 is used in the study of neurological diseases, histamine H3 receptor antagonist. |
|
T23190 |
Proxyfan oxalate
|
|
Others
|
|
histamine H3 receptor ligand |
|
T22863 |
Immepip dihydrobromide
|
|
Others
|
|
Immepip dihydrobromide is a histamine H3 receptor agonist. |
|
T22866 |
Impentamine dihydrobromide
|
|
Others
|
|
Impentamine dihydrobromide is a histamine H3 receptor antagonist. |
|
T23841 |
Burimamide
|
|
|
|
Burimamide is an antagonist of histamine. It appears to block both H2 and H3 histamine receptors. |
|
T26480 |
A331440
|
A-331440,A331440 free base,A 331440 |
|
|
A331440 is an modulator of L-histidine and histamine H3 receptor. |
|
T26643 |
Aplysamine-1
|
Aplysamine |
|
|
Aplysamine-1 is an antagonist of histamine H3 receptor. |
|
T23038 |
Nα-Methylhistamine dihydrochloride
|
|
Others
|
|
Nα-Methylhistamine dihydrochloride is a histamine H3 receptor agonist. |
|
T70112 |
GT-2227
|
|
|
|
GT-2227 is a histamine H3 receptor antagonist. |
|
T29043 |
UCL-1972
|
UCL 1972 |
|
|
UCL-1972, a Histamine H3 Receptor Antagonist, used to treat cognitive disorders. |
|
T69756 |
GT-2331
|
|
|
|
GT-2331 is a histamine H3 receptor antagonist. |
|
T70111 |
GT-2394
|
|
|
|
GT-2394 is a histamine H3 receptor agonist. |
|
T27473 |
GSK334429
|
GSK-334429,GSK 334429 |
|
|
GSK334429 is an antagonist of histamine H3 receptor. |
|
T24698 |
(R)-(-)-α-Methylhistamine dihydrochloride
|
HISTAMINE DIHYDROCHLORIDE R(-)-A-METHYL |
|
|
R(-)-alpha-Methylhistamine 2HCl is an effective and selective agonist of the H3 histamine receptor. |
|
T12054 |
MK-0249
|
|
Histamine Receptor
|
|
MK-0249 is a potent antagonist of histamine H3 receptor (human H3, Ki : 1.7 nM). |
|
T22878 |
JNJ 10181457 dihydrochloride
|
|
Others
|
|
JNJ 10181457 dihydrochloride is a Histamine H3 receptor antagonist. |
|
T69737 |
SCH-79687
|
|
|
|
SCH-79687 is a histamine antagonist selective for the H3 subtype. This H3 antagonist may play a role in allergic rhinitis. |
|
T27022 |
Cipralisant maleate
|
GT-2331,Cipralisant maleate. trade name Perceptin,GT 2331,GT2331 |
|
|
Cipralisant maleate is a potent, selective Histamine H3 receptor antagonist. |
|
T28184 |
NNC-38-1049
|
NNC381049,NNC 38-1049,NNC38-1049,NNC 381049,NNC-381049 |
|
|
NNC-38-1049 is a novel selective antagonist of histamine H3. |
|
T71605 |
APD-916 dicitrate
|
|
|
|
APD-916 dicitrate is a potent and selective inverse agonist of the histamine H3 receptor. |
|
T19762 |
Clobenpropit 2HBr
|
VUF-9153,VUF 9153,Clobenpropit Dihydrobromide,VUF9153 |
|
|
Clobenpropit 2HBr is a histamine H3 receptor antagonist. It has neuroprotective effects via stimulation of GABA release in the brain. |
|
T12416 |
PF-03654746 Tosylate
|
|
Histamine Receptor
|
|
PF-03654746 Tosylate is selective antagonist of histamine H3 receptor with high brain penetration. |
|
T71270 |
ZEL-H16
|
|
|
|
ZEL-H16 is an agonist of the histamine H3 receptor. |
